Select Recent Publications

  1. 1. Shajan, B. et al. Functional implications of the C182F TAAR1 variant identified in patients with schizophrenia. Genomic Psychiatry 2, 42–48 (2026). https://doi.org/10.61373/gp026r.0006
  2. 2. Nair, P. C., Shajan, B. & Bastiampillai, T. Newly identified structures of trace-amine associated receptor-1 (TAAR1) will aid discovery of next generation neuropsychiatric drugs. Molecular Psychiatry 29, 1925–1928 (2024). https://doi.org/10.1038/s41380-024-02466-z
  3. 3. Shajan, B. et al. Trace amine associated receptor 1: predicted effects of single nucleotide variants on structure-function in geographically diverse populations. Human Genomics 18, 61 (2024). https://doi.org/10.1186/s40246-024-00620-w
  4. 4. Shajan, B., Bastiampillai, T., Hellyer, S. D. & Nair, P. C. Unlocking the secrets of trace amine-associated receptor 1 agonists: new horizon in neuropsychiatric treatment. Frontiers in Psychiatry 15 (2024). https://doi.org/10.3389/fpsyt.2024.1464550
  5. 5. Shajan, B., Bastiampillai, T. & Nair, P. C. The association between trace amine-associated receptor 1 (TAAR1) genetic mutations and neuropsychiatric disorders. Genomic Psychiatry 1, 17–20 (2024). https://doi.org/10.61373/gp024v.0058
  6. 6. Tibrewal, P. et al. Does clozapine treat antipsychotic-induced behavioural supersensitivity through glutamate modulation within the striatum? Molecular Psychiatry 28, 1839–1842 (2023).
  7. 7. Nair, P. C. et al. Trace amine-associated receptor 1 (TAAR1): molecular and clinical insights for the treatment of schizophrenia and related comorbidities. ACS Pharmacology & Translational Science 5, 183–188 (2022).
  8. 8. Nair, P. C. et al. Binding of SEP-363856 within TAAR1 and the 5HT1A receptor: implications for the design of novel antipsychotic drugs. Molecular Psychiatry 27, 88–94 (2022).
  9. 9. Nair, P. C., McKinnon, R. A., Miners, J. O. & Bastiampillai, T. Binding of clozapine to the GABAB receptor: clinical and structural insights. Molecular Psychiatry 25, 1910–1919 (2020).